http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1179435-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25f5e60cca882cd756ee1cd36c3fef16 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-868 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-815 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
| filingDate | 1967-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1970-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1179435-A |
| titleOfInvention | Stable Reagent for the Detection of Rheumatoid Arthritis |
| abstract | 1,179,435. Determination of rheumatoid factor. ORTHO PHARMACEUTICAL CORP. 18 May, 1967 [17 June, 1966], No. 23157/67. Heading B1X. A reagent for determining rheumatoid factor comprises a suspension in a polar liquid of solid synthetic polymer particles having average diameter 0.15 to 14 microns and coated with rabbit gamma-globulin which has been subjected to the action of proteolytic enzymes. The polymer particles are preferably polystyrene particles average diameter 0.81 micron; acrylic polymer is mentioned. The enzyme is preferably trypsin, chymotrypsin or papain; also mentioned are fungal proteases and pepsin. In preparing the reagent, the rabbit gamma-globulin in phosphate or bromate buffer pH 8.6 is mixed with the proteolytic enzyme then the treated gamma-globulin is added to the particle suspension. The suspension may then be heated, for example to 50C for 7 to 10 days to complete the treatment of the gamma-globulin. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0107861-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2521303-A1 |
| priorityDate | 1966-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.