http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1164705-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7965c8407e888a0afba1edeea1e04845 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1967-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1164705-A |
| titleOfInvention | Preparation of Delta<7>-Dehydro Steroids |
| abstract | 1,164,705. 14α- Hydroxy - #<SP>7</SP> - 6 - keto - Steroids. ZEOCON CORP. 31 May, 1967 [31 May, 1966], No. 25078/67. Heading C2U. 14α - Hydroxy - #<SP>7</SP> - 6 - keto - steroids are prepared from #<SP>8(14)</SP>-6-keto-steroids either by irradiated oxidation to 14α-hydroperoxy-#<SP>7</SP>-6- keto-steroids and mild reduction of these, or by epoxidation to 6-keto-8α,14α-oxido-steroids and treatment of these with acid or base. Examples describe the preparation of 2#,3#-diacetoxy-6- keto - 14α - hydroxy - 22,23 - bisnor - 5α - chol - 7-enoic acid methyl ester, the corresponding 5#-compound and the corresponding 5α-ol and its acetate; 2#,3#,14α,22,25-pentahydroxy-5#- cholest - 7 - en - 6 - one; and 2#,3# - diacetoxy- 5α,14α,22 - trihydroxy - 6 - keto - chol - 7 - ene 24-carboxylic acid 22-lactones. #<SP>8(14)</SP>-6-keto-steroids are prepared by from 6-keto-7-bromo-steroids, prepared in turn by bromination. 2#,3# - diacetoxy 5α,22 - dihydroxy - 6 - ketocholane 24-carboxylic acid 22-lactone is prepared by the sequence methyl 3#-hydroxy-22,23-bisnorchol - 5 - enoate # 3# - hydroxy 23 - methylsulphinyl - 24 - norchol - 5 - en - 22 - one # methyl 3# - hydroxy - 22 - keto - 23 - methylsulphinylchol - 5 - en - 25 - oate # 3#,22 - dihydroxychol - 5 - en - 25 - oic acid 22 - lactone # 3 - acetate # 3#,5α,6#,22 - tetrahydroxycholane 24 - carboxylic acid 22 - lactone # 3#,5α,22 - trihydroxy - 6 - ketocholane 24 - carboxylic acid 22-lactone # 3-tosylate # 5α,22- dihydroxy - 6 - ketochol - 2 - ene 24 - carboxylic acid methyl ester # 2#,3#,5α,22 - tetrahydroxy- 6-ketocholane 24-carboxylic acid methyl ester # required product. |
| priorityDate | 1966-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID406903349 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458393636 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID175 |
Total number of triples: 15.