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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-10
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filingDate 1966-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1969-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1156719-A
titleOfInvention Improvements in or relating to the production of Substituted Amines
abstract 1,156,719. Purine derivatives. W. OTTO, and L. SAILER, [trading as GEROT-PHARMAZEUTIKA DR. WALTER OTTO K.G.]. 9 Dec., 1966 [10 Dec., 1965; 22 March, 1966], No. 55188/66. Heading C2C. Compounds of general Formula I wherein R 1 is H or alkyl; R 2 is H or OH; R 3 and R 4 are H if R 1 is alkyl and R 2 = OH, or are each halogen, alkyl or OH possibly etherified; A is Th.CH.CH 2 - or ThCH 2 .CH(R 5 ).CH 2 -, wherein Th is a theobromine or theophylline residue and R 5 is H or, if one of R 1 to R 4 is not H, OH, and Z is A or may be alkyl or H when A is Th.CH 2 .CH(OH).CH 2 -, are prepared by reacting a compound of formula wherein R 6 is H or alkyl either with a compound of formula A-halogen or firstly with epichlorohydrin and then with theobromine and/or theophylline. The following compounds are claimed as novel:-Norephedrin - N - hydroxypropyltheophylline, norephedrin - N - di(hydroxypropyltheophylline), ephedrin - N - hydroxypropyltheophylline and N-[2-hydroxy-3-(theophylline - 7) - propyl] - 2 - hydroxy - 2 - (3<SP>1</SP> - hydroxyphenyl)-ethylamine HCl.
priorityDate 1965-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.