http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1151971-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c4cb9b5558ad97d3acc0db1113f7727 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-33 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 |
| filingDate | 1967-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1151971-A |
| titleOfInvention | Piperonyl-Piperazine Derivatives and Process for Preparing Them |
| abstract | 1,151,971. Piperonyl-piperazines. SCIENCE UNION ET CIE, SOC. FRANCAISE DE RECHERCHE MEDICALE. 29 June, 1967 [30 June, 1966], No. 30012/67. Heading C2C. Piperonyl-piperazines of general Formula I and their physiologically acceptable salts in which Ar is a phenyl, tolyl, xylyl or fluorophenyl radical and A is -CH 2 CH 2 CH 2 CO-, -CH 2 - CH(CH 3 )-CO- or -CH 2 CH 2 CH 2 CHOH-, the -CO- or -CHOH- group being joined directly to Ar, are prepared by reacting 1- piperonyl-piperazine with a propiophenone of the general formula Ar.CO.CH(CH 3 ).CH 3 in the presence of paraformaldehyde and hydrochloric acid, or with an aroylalkyl chloride of formula Ar.CO.(CH 2 ) 3 .Cl, and the carbonyl derivative so obtained may be reduced by lithium aluminium hydride. Pharmaceutical compositions comprise a compound I together with a suitable excipient, are administered orally, rectally or parenterally and possess neuroleptic, vasodilatory, adrenolytic and anti-emitic activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2527605-A1 |
| priorityDate | 1966-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.