http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1151862-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c8514878053ed09557f9014c1602409 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-22 |
| filingDate | 1965-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38dcf6e5a6c0c31ba8a907d05f8c6041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3465d459c771ec1aa6a79507709304e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_673672400f541541e72918cf90578f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0306d461a190695d05cd51da1c91f7f |
| publicationDate | 1969-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1151862-A |
| titleOfInvention | Fluorinated and/or Chlorinated Heterocyclic Compounds |
| abstract | 1,151,862. Chlorinated and fluorinated isoquinolines. IMPERIAL SMELTING CORP. (N.S.C.) Ltd. 27 June, 1966 [24 May, 1965], No. 21975/65. Heading C2C. [Also in Division C4] The invention comprises fully chlorinated and/or fluorinated isoquinoline, and derivatives thereof in which 1 or 2 halogen atoms are replaced by C 1-6 alkyl, C 1-6 perhaloalkyl, hydroxy, alkoxy, amino (possibly substituted) or hydrazino groups. Heptachloroisoquinoline (I) is prepared by reacting isoquinoline -AlCl 3 complex with Cl 2 , and reacting the hexachloroisoquinoline so formed with PCl 5 ; I is converted to heptafluoroisoquinoline (II) by heating with dry alkali metal fluoride when 4-chlorohexafluoroisoquinoline is also isolated. II, also formed by reacting hexafluoroisoquinoline - 1 - diazonium fluoride with H 3 PO 2 , reacts with the following reagents giving the products indicated in parentheses:-(a) NaOMe (1-methoxyhexafluoroisoquinoline and 1,6-dimethoxypentafluoroisoquinoline, both of which give 5,6-difluoro-2- methoxypyridine - 3,4 - dicarboxylic acid with KMnO 4 ); (b) NH 3 (1-aminohexafluoroisoquinoline); (c) N 2 H 4 (1-hydrazinohexafluoroisoquinoline); (c) LiAlH 4 (3,4,5,6,7,8-hexafluoroisoquinoline); (d) aq. NaOH, or KOH/Me 3 COH (1 - hydroxyhexafluoroisoquinoline and the tautomeric quinolone); (e) LiBu (1- and 6- butylhexafluoroisoquinoline). Also prepared are N-methylhexafluoro- 1 -isoquinolone, benzaldehyde - hexafluoroisoquinolyl - 1 - hydrazone, 1 - trifluoroacetylaminohexafluoroisoquinoline, 1 . amino - 6 - methoxypentafluoroisoquinoline, 6 - methoxyhexafluoroisoquinoline and 4- ohloro-1-methoxypentafluoroisoquinoline. Specification 980,248 is referred to. |
| priorityDate | 1965-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.