http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1150241-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-02 |
| filingDate | 1966-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1150241-A |
| titleOfInvention | A Method for the Production of Ribonucleoside-5'-Phosphates |
| abstract | 1,150,241. Ribonucleoside 51-phosphates. TAKEDA CHEMICAL INDUSTRIES Ltd. 27 May, 1966 [29 May, 1965], No. 23807/66. Heading C2C. Ribonucleoside 5<SP>1</SP>-phosphates are produced by reacting a ribonucleoside with an aliphatic ketone having 3 to 6 carbon atoms, or an aromatic aldehyde, and PCl 3 in the presence of water and oxygen, and subsequently hydrolysing the resulting product. Specified nucleosides are inosine, adenosine, cytidine and uridine. The ribonucleoside is preferably dissolved in a large excess of ketone and PCl 3 and water are then added in molar ratios of 10 to 100 of PCl 3 : 2 to 20 of water: 1 of ribonucleoside. The reaction is preferably carried out by first adding water and a little of the PCl 3 to the ribonucleoside solution, and then adding the remaining PCl 3 to form the 5<SP>1</SP> phosphate derivative in the presence of oxygen or air. The preferred reaction temperature is 0 to 10‹ C. The hydrolysis may suitably be performed by adding the product to ice-water, and then adding alkali until a pH of 1 to 2 is reached, and warming to about 60‹ C. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10219720-A1 |
| priorityDate | 1965-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.