http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1136856-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 |
filingDate | 1967-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1968-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1136856-A |
titleOfInvention | Process for the manufacture of 4-halogeno-1,2-‡; 6,7-ß-bismethylene-í¸-3-keto-steroids |
abstract | 1,136,856. 4 - Halogeno - 1,2α:6,7# - bismethylene - #<SP>4</SP> - 3 - keto - steroids. SCHERING A.G. 21 Aug., 1967 [25 Aug., 1966], No. 38441/67. Heading C2U. 4- Halogeno - 1,2α: 6,7# - bismethylene - #<SP>4</SP>-3- keto-steroids, novel when having the formula (wherein X is F, Cl or Br; Y is H 2 or O; Z is αH(#-OR); α-OR(#-COCH 3 ) or α-OH (#-COCH 2 OH) in the form of the bismethylenedioxy derivative, R being H or acyl), are prepared from the corresponding 4-halogeno-#<SP>1</SP>'<SP>4</SP>'<SP>6</SP>- 3-keto-steroids and methyleneating agents. Preferred agents are dimethylmethylenesulphonium oxide or diazomethane (which forms fused-on pyrazoline rings which are subsequently decomposed). 4 - Chloro - 17,20: 20,21 - bismethylenedioxy- #<SP>1</SP>'<SP>4</SP>'<SP>6</SP> - pregnatriene- 3,11 - dione is prepared by chlorination of the corresponding 4-unsubstituted steroid. The steroids of the invention, which may, for example, have gestagenic and ovulation-inhibiting activity, be incorporated in pharmaceutical compositions. |
priorityDate | 1966-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.