http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1135781-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcc98b42717527a355228452491869d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-18 |
| filingDate | 1966-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1968-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1135781-A |
| titleOfInvention | Benzodiazepines and processes for the production thereof |
| abstract | 1,135,781. Benzodiazepines. ETABS. CLINBYLA. 7 Jan., 1966 [9 Jan., 1965], No. 945/66. Heading C2C. Novel 5-substituted benzodiazepines having the general formula in which R<SP>1</SP> is a phenyl group or a group having the general formula in which each of R<SP>5</SP> and R<SP>6</SP> is a hydrogen or chlorine atom or an alkyl or aralkyl group or R<SP>5</SP> and R<SP>6</SP> taken together with the carbon atom to which they are attached represent a cycloalkyl group and R<SP>7</SP> is a hydrogen or chlorine atom, R<SP>2</SP> is a hydrogen or chlorine atom, R<SP>3</SP> is a hydrogen atom or an alkyl group having 1-5 carbon atoms and R<SP>4</SP> is a hydrogen or halogen atom or an alkyl, alkoxy, trifluoromethyl or nitro group, R<SP>2</SP> being a halogen atom when R<SP>1</SP> is a phenyl group, are obtained by treating a benzodiazepine having the general formula in which R<SP>8</SP> is a phenyl group or a group of the general formula with a hypochlorite, e.g. a metal or organic hypochlorite, and if desired in a compound in which R<SP>8</SP> is a group of the formula -HCR<SP>5</SP>R<SP>6</SP> heating the product in solution in a non-alcoholic solvent to effect rearrangement. Pharmaceutical compositions containing the above compounds which have a sedative action on the central nervous system or antiphlogistic activity are administered orally. |
| priorityDate | 1965-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.