http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1132287-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
filingDate | 1966-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1968-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1132287-A |
titleOfInvention | Antibiotic compositions |
abstract | 1,132,287. Coumermycin; preparing salts. F. HOFFMANN-LA ROCHE & CO. A.G. 30 Sept., 1966 [4 Oct., 1965], No. 43785/66. Heading C2A. [Also in Division A5] The N-methyl-glucamine salt of coumermycin, having the formula wherein X<SP>1</SP> and Y<SP>1</SP> are each a 5-methyl-pyrroyl- (2) group, a pyrroyl-(2) group or a hydrogen atom, are prepared by reacting the free acid of coumermycin with two molar proportions of the amine in aqueous ethanol; the resulting solution of the salt is freeze-dried. The sodium salt of coumermycin is prepared in a similar manner, by addition of sodium hydroxide solution to an aqueous ethanolic coumermycin solution, the salt being isolated by freeze-drying. The salts are for use in pharmaceutical compositions (see Divisions A5-A6); the N-methyl glucamine may be admixed with the coumermycin or a salt thereof to render the antibiotic water-soluble, or the pre-formed N- methyl glucamine-antibiotic salt may be used. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4213903-A |
priorityDate | 1965-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.