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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
filingDate 1966-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1968-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1132287-A
titleOfInvention Antibiotic compositions
abstract 1,132,287. Coumermycin; preparing salts. F. HOFFMANN-LA ROCHE & CO. A.G. 30 Sept., 1966 [4 Oct., 1965], No. 43785/66. Heading C2A. [Also in Division A5] The N-methyl-glucamine salt of coumermycin, having the formula wherein X<SP>1</SP> and Y<SP>1</SP> are each a 5-methyl-pyrroyl- (2) group, a pyrroyl-(2) group or a hydrogen atom, are prepared by reacting the free acid of coumermycin with two molar proportions of the amine in aqueous ethanol; the resulting solution of the salt is freeze-dried. The sodium salt of coumermycin is prepared in a similar manner, by addition of sodium hydroxide solution to an aqueous ethanolic coumermycin solution, the salt being isolated by freeze-drying. The salts are for use in pharmaceutical compositions (see Divisions A5-A6); the N-methyl glucamine may be admixed with the coumermycin or a salt thereof to render the antibiotic water-soluble, or the pre-formed N- methyl glucamine-antibiotic salt may be used.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4213903-A
priorityDate 1965-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 22.