http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1130370-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634715a790f7ef0163a61e9f364bebcd
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00
filingDate 1965-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3341b88ee0b159f509a4aed19e8d166d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53480042396a62a9d4a601898e23062b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f3858ca91f7a7cd980f6907fd18f46
publicationDate 1968-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1130370-A
titleOfInvention Esters of 6-aminopenicillanic acid
abstract 1,130,370. 6 - Aminopenicillanic acid esters. ASTRA A.B. 8 Nov., 1966 [12 Nov., 1965], No. 48208/65. Heading C2A. The invention relates to esters of 6-aminopenicillanic acid of formula where R represents a phenacyl group which is either unsubstituted or substituted with one or more halogen atoms, C 1-6 alkyl, C 1-6 alkoxy or NO 2 groups, and their acid addition salts. The esters are prepared by reacting a salt of 6-aminopenicillanic acid and an organic or inorganic base, e.g. the sodium or triethylamine salt, with a compound of formula X-R, wherein R is as defined above and X is halogen, e.g. bromine or an organic sulphonic acid residue, e.g. p-toluene sulphonic acid residue. The resulting ester is reacted with an acid to produce the acid addition salt. Penicillins are produced by acylating the 6-amino group of the resultant ester. The phenacyl group of the penicillin may be removed by treatment with sodium or potassium thiophenoxide. Typical esters are the phenacyl, p-bromophenacyl, pmethoxyphenacyl and p-nitrophenacyl esters of 6-aminopenicillanic acid.
priorityDate 1965-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 35.