http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1124920-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01G25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-46 |
| filingDate | 1967-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7258d435343bf1d2e131fbf0a75079e4 |
| publicationDate | 1968-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1124920-A |
| titleOfInvention | Penicillins and a process for the preparation thereof |
| abstract | The invention relates to 6-(31-methyl-41-furazanacetamido) penicillanic acid of formula <FORM:1124920/C2/1> and non-toxic pharmaceutically acceptable salts thereof, e.g. sodium, calcium, aluminium, ammonium and amine salts. The compounds are prepared by acylating 6-aminopenicillanic acid, or a salt thereof, with an acylating derivative of an acid of formula <FORM:1124920/C2/2> 3-methyl-4-furazanacetic acid is prepared by (a) treating 3-methyl-4-furazancarbonyl chloride with diazomethane to form the diazoketone, (b) treating the diazoketone with benzyl alcohol and N,N1-dimethylaniline to form the benzyl ester of 3-methyl-4-furazanacetic acid, and (c) hydrolysing the benzyl ester with mineral acid. The starting material for (a) is produced by treating 3-methyl-4-furazancarboxylic acid with thionylchloride. The penicillins are effective against gram-positive and gram-negative bacteria and may be administered orally to man and animals, e.g. for the treatment of mastitis in cattle or as a nutritional supplement in animal feeds. The penicillins may be formulated into pharmaceutical compositions. |
| priorityDate | 1966-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.