http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1112076-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d629f98a51b15993f56f9e04fdea237f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate | 1966-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1968-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1112076-A |
| titleOfInvention | Method for introducing a hydroxy group into a steroid molecule containing a keto group |
| abstract | The invention comprises a process for introducing a hydroxy group on to a tertiary carbon atom adjacent to a keto group in a steroid molecule by reacting the steroid with oxygen in a mixture containing a strongly basic enolizing agent and a reducing agent capable of reducing the hydroperoxy group formed and substantially insensitive to the oxidizing agent under the reaction conditions. Enolizing agents specified are alkali metal alkoxides, hydrides and amides, hindered alkali metal alkyl derivatives and tetra-alkyl ammonium hydroxides. Reducing agents specified are tri-hydrocarbonyl phosphines, tri-alkyl phosphites and salts of alkyl sulphinic acids. Exemplified reactions introduce a -hydroxy groups at the 9 and 17-positions, and 5,8 and 14-hydroxylations are also mentioned. |
| priorityDate | 1965-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.