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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-886
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28
filingDate 1965-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1968-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-1108779-A
titleOfInvention A process for the production of tetracycline by fermentation
abstract Tetracycline is produced by the submerged fermentation in a liquid medium containing assimilable carbon and nitrogen and inorganic salts under aerobic conditions of micro-organisms of the genus Streptomyces capable of producing both chlorotetracycline and tetracycline, by the addition to the fermentation medium of at least one chlorination inhibitor corresponding to the general formula <FORM:1108779/C2/1> wherein Z is H, OH or Cl; X is halogen, preferably Cl or iodine, or is akyl, aryl, H, NH2 or NO2; and Y is H, Cl, NH2 or COOH. Alternatively, X and Y may be members of a second 5- or 6-membered aromatic or heterocyclic ring e.g. 2,6 - dichloro - 7 - methyl purine. Other specified inhibitors are 2,4-dichloro-pyrimidine, 5 - iodo - 2,4 - dichloro pyrimidine, 5 - methyl-2,4,6 - trichloro - pyrimidine and 5 - methyl-2,4-dichloropyrimidine.
priorityDate 1964-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.