http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1107036-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_364b3cbf956b10ca710b6407d25b6fd0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C62-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 1964-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_565c2c9b55a21ae9aa5ec230640c1358 |
| publicationDate | 1968-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1107036-A |
| titleOfInvention | Esters of dibenzocycloheptenyl-carboxylic acids |
| abstract | <FORM:1107036/C2/1> <FORM:1107036/C2/2> <FORM:1107036/C2/3> Novel esters of the Formula I, wherein X represents an ethylene or ethenylene radical, R1 and R2, the same or different, represent a hydrogen or halogen atom or C1- 5 alkyl group, and R3 represents a saturated polycyclic nitrogen-containin heterocyclic radical with at most 12 carbon atoms attached through carbon to the oxygen atom, and acid addition salts thereof, are prepared by reacting the corresponding free acid of the Formula II, or a reactive derivative thereof, with an alcohol of the formula R3OH, by reacting said acid or an alkali metal salt thereof with a halide of the formula R3Y (wherein Y represents a halogen atom), or by esterifying said acid with a C1- 5 alkanol and transesterifying the resultant ester with an alcohol of the formula R3OH. Carboxylic acids of the Formula II may be prepared by reacting a ketone of the Formula III with an alkali metal followed by carbon dioxide. Therapeutic compositions with anti-arrhythmic and atropine-like properties, which may take forms suitable for oral and parenteral administration, comprise compounds of the Formula I or their non-toxic acid addition salts, together with a suitable carrier. |
| priorityDate | 1964-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.