http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1100675-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 |
| filingDate | 1965-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a5e8a90cd5a0a4b795199d10fad9003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ce34161d83e98999b1e48b8439d4d79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae7eaba2dae865f1b465e74af65ad181 |
| publicationDate | 1968-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1100675-A |
| titleOfInvention | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof |
| abstract | The invention comprises compounds of the general formula <FORM:1100675/C2/1> (wherein R1 and R2 represent C1- 7 alkyl groups and the broken lines denote that they are optional substituents) and acid addition salts thereof, pharmaceutical preparations containing them, and their preparation by reacting a ketone of the formula <FORM:1100675/C2/2> either with an amino acid of the formula <FORM:1100675/C2/3> or a C1- 7 alkyl ester thereof, or with a haloacyl halide of the formula <FORM:1100675/C2/4> (wherein X and Y represent halogen atoms), treating the resulting [2-(a -haloalkanoylamino)-benzoyl]-pyridine with ammonia and cyclizing the resulting [2-(a -aminoalkanoylamino) benzoyl]-pyridine, or with benzyloxycarbonylglycine, treating the resulting (2-benzyloxycarbonylglycylaminobenzoyl) -pyridine with a hydrobromic acid-acetic acid mixture and cyclizing the resulting (2-glycylaminobenzoyl)-pyridine, optionally followed in each case by acid addition salt formation. The preparation of the ketone starting materials is described. The compounds of the invention are sedatives, muscle relaxants and anticonvulsants and may be administered in the form of pharmaceutical preparations containing them, with or without other (unspecified) active ingredients, in association with a carrier. |
| priorityDate | 1965-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.