http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1097167-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-28 |
| filingDate | 1966-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1097167-A |
| titleOfInvention | 3-hydroxy-6-oxo-n-phenethylmorphinan compounds and their production |
| abstract | Novel 3 - hydroxy - 6 - oxo - N - phenethyl-7 - dehydromorphinan(cis) and 3 - hydroxy - 6-oxo - N - phenethylmorphinan(cis) and acid addition salts thereof are prepared by subjecting the corresponding 3-methoxy-6-oxo-N-phenethylmorphinan(cis) compounds to hydrolytic fission, followed by optional conversion to an acid addition salt. Pharmaceutical compositions comprising as active ingredient 3-hydroxy-6-oxo-N-phenethyl-7 dehydromorphinan(cis), 3-hydroxy-6-oxo-N-phenethylmorphinan(cis) or acid addition salts thereof in combination with a pharmaceutical carrier are useful as analgesic agents. 3 - Methoxy - 6 - oxo - N - phenethyl - 7 - dehydromorphinan(cis) and 3 - methoxy - 6 - oxo-N-phenethylmorphinan(cis) are prepared by reacting the corresponding N-methyl compounds with cyanogen bromide, treating the resulting N-cyano compounds with hydrochloric acid and reacting the resulting N-unsubstituted compounds with phenethyl bromide. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6163658-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4668685-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016182840-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766864-B2 |
| priorityDate | 1966-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.