http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1089788-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30432c021c19453629a3b69ce104640e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1966-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1089788-A |
| titleOfInvention | Process for the production of steroidal lactone compounds and intermediates thereof |
| abstract | Novel steroids of the Formula (IV) are prepared from steroids of the Formula (II) by reaction of the latter with a compound M-CH2-R1 (M is an alkali metal) and subsequent hydrolysis by heating with water or water and an organic acid; and are converted to steroids of the Formula (I) by hydrolysis with a strong acid or alkali. <FORM:1089788/C2/1> <FORM:1089788/C2/2> <FORM:1089788/C2/3> In these formulae R1 is carboxamido which may be substituted, carboalkoxy or cyano; Z is carbonyl, A a double bond and B a single bond or Z is b -hydroxymethylene, A a single bond and B a double bond; W is b -OH and Y is a single bond, or W is -NR2R3 on which R2 and R3 are C1- 4 alkyl or -NR2R3 is pyrrolidino, piperidino or morpholino and Y is a double bond. Steroids (IV) which are D 5-3-ols may be oxidized by the Oppenauer method to the D 43-ones before conversion to steroids (I.) Steroids (II) are described and claimed in Specification 1,066,658. |
| priorityDate | 1965-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.