http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1085922-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fa5e83135b2b437073add3483347517 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-48 |
| filingDate | 1965-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1085922-A |
| titleOfInvention | Improvements in and relating to therapeutic compositions containing 2-amino-oxazolin-4-one derivatives, novel derivatives of this type and process for preparing same |
| abstract | The invention comprises compounds of the formula <FORM:1085922/C2/1> wherein R represents an alkyl group or a substituted or unsubstituted phenyl group, A represents a piperidino, pyrrolidino, morpholino or piperazino ring, each of these rings possibly being substituted by one or two C1- 6 alkyl groups on nuclear carbon atoms and R1, when A is a piperazino ring, is attached to the second nitrogen atom of said ring and is a hydrogen atom or a substituted or unsubstituted alkyl, acyl, aryl, alkaryl or aralkyl group, with the proviso that when R is the phenyl group, A-R1 is not a piperidino, N-methyl piperazino or morpholino group; acid-addition salts thereof; and their preparation by reacting a 5-substituted-2-amino-oxazolin-4-one of the formula <FORM:1085922/C2/2> with a heterocyclic base of the formula <FORM:1085922/C2/3> 2 - Amino - oxazolin - 4 - ones of the Formula II, in which R is an alkyl group having 4 or more carbon atoms, are prepared by reacting a compound of the formula R.CH(OH).COOR2, wherein R is an alkyl group having 4 or more carbon atoms and R2 is a C1- 6 alkyl group, with guanidine.ALSO:Pharmaceutical compositions having anti-inflammatory, anti-pyretic and analgesic properties, for oral, rectal or parenteral administration, comprise a compound of the formula: <FORM:1085922/A5-A6/1> wherein R represents an alkyl group or a substituted or unsubstituted phenyl group, A represents a piperidino, pyrrolidino, morpholino or piperazino ring, these rings possibly being substituted by one or two C1-6 alkyl groups or nuclear carbon atoms and R1, when A is a piperazino ring, is attached to the second nitrogen atom and is a hydrogen atom or a substituted or unsubstituted alkyl, acyl, aryl, alkaryl or aralkyl group. |
| priorityDate | 1965-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.