http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1080324-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c4cb9b5558ad97d3acc0db1113f7727 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 |
| filingDate | 1964-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df5584a3ef50a42847f178d900361f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dead9c4e72d341fba60253a31ce37059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8825cba8c3caa1dc91d90c30bdfd52 |
| publicationDate | 1967-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1080324-A |
| titleOfInvention | New piperazine derivatives and process for preparing them |
| abstract | Novel 1 - (1,1 - dialkyl - 2 - phenyl - ethyl)-piperazines of the general formula <FORM:1080324/C2/1> where X represents H, F, Cl, Br, C1- 5 alkyl, C1- 5 alkoxy or halogenomethyl, and R1 and R2 are C1- 4 alkyl, the same or different and acid addition salts thereof, are prepared by heating a 1-(1,1-dialkyl-2-phenethyl)-amine with water and ethylene oxide, treating the resulting bis-hydroxyalkylamine with thionyl chloride, forming a piperazine ring by treating the resulting bis-chloro-alkylamine with benzylamine and hydrogenating the resulting benzylpiperazine compound. 1 - Phenyl - 2 - methyl - 2 - amino - propanes where the phenyl radical is substituted as above are prepared from 1-phenyl-2-methylpropenes by reacting these with sodium cyanide in acetic acid and sulphuric acid and hydrolysing the resulting N-formylamino compounds. Therapeutic compositions useful as analgesics and anorexia-inducing agents contain as the active ingredient a compound of the general formula above, or an acid addition salt thereof, in admixture with a pharmaceutical carrier. |
| priorityDate | 1964-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.