http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1079271-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-92 |
| filingDate | 1964-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1079271-A |
| titleOfInvention | Imidazole derivatives |
| abstract | Novel compounds of formula <FORM:1079271/C2/1> wherein R1 represents an alkyl group containing 1-6 carbon atoms, and R2 is a hydrogen atom, or an alkyl group having 1-5 carbon atoms, and acid-addition salts thereof, are prepared by reacting in the absence of a basic condensing agent an N1-unsubstituted nitroimidazole with a compound of formula Z-CH2-CH(R1)-OY wherein Z represents the acid residue of a reactive ester and Y represents a hydrogen atom or a radical which protects the hydroxyl group during the reaction, and is readily replaceable by a hydrogen atom, and, where Y is other than a hydrogen atom liberating the hydroxyl group, or by reacting the N1-unsubstituted nitroimidazole with a 1,2-alkyleneoxide in a liquid medium containing, or consisting of, at least one organic acid which is a solvent for the nitroimidazole. Therapeutic compositions having amoebicidal or trichomonacidal activity which may be administered orally, parenterally or locally contain as active ingredient compounds of Formula I above or a non-toxic acid addition salt thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2195536-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4925952-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5574167-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3987053-A |
| priorityDate | 1963-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.