http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1077392-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d037bc74e34c7d73dd883f208aef0518 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1965-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5a716a537afe7f6b8a6bf2d0f7a448a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04c6c956ff8aa397acf13f23bfc84f0e |
| publicationDate | 1967-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1077392-A |
| titleOfInvention | New steroids |
| abstract | The invention comprises steroidal [17a , 16a -d]-oxazolines of the formula <FORM:1077392/C2/1> and the D 4 and D 5(6) counterparts thereof, in which R is O, H(b -OH) or H(b -O Acyl), R1 is H2 or O, and R11 is H, an alkyl group having up to eight carbon atoms or an alkyl, aralkyl or aryl group, and a process for the production of a steroidal [17a , 16a -d]-21-R11-oxazoline of the pregnane series which comprises catalytically hydrogenating a 16a -acyloxy-17a -azido-steroid of the pregnane series. The 16a -acyloxy-17a -azido starting steroids may be obtained by refluxing a 16b , 17b -epoxy-20-keto-17a -pregnane steroid with sodium azide in the presence of an acid capable of liberating hydrazoic acid from its salts to obtain the corresponding 16a -hydroxy-17a -azido steroid and acylating the latter. 16a -Hydroxy-17a -acylamido pregnanes formed as by-products may be also converted into the desired oxazolines by treatment in benzene in the presence of an acidic catalyst, e.g. p-toluenesulphonic acid. Pharmaceutical compositions containing the above compounds are employed as progestinics and anti-inflammatory agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101177443-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3146785-A1 |
| priorityDate | 1965-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.