http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1077173-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 |
| filingDate | 1965-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_764e794e2d1a1dc221b3cf982be80a8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4493f47d874415e4bacccd5bd59507f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e56396a77706c58567ae99f6f1861f8d |
| publicationDate | 1967-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1077173-A |
| titleOfInvention | Substituted alkylene piperidines and methods of preparation thereof |
| abstract | Novel piperidines of the formula <FORM:1077173/C2/1> wherein R1 is C1-C6 alkyl, R2 is hydrogen, (C1-C12) alkyl, aralkyl or cycloalkyl, R3 is a substituted phenyl radical, an aromatic heterocyclic radical of at least 5 ring atoms and containing not more than 4-hetero atoms the rest being carbon, or the radical R4CO, wherein R4 is a phenyl, biphenyl, halophenyl, dichlorophenyl, phenyltriazolyl, phenylazophenyl, benzyloxy, nitrofuryl, alkoxy or trihalomethyl group, n is 3 or 4 are obtained by reacting a compound of the formula <FORM:1077173/C2/2> wherein R1, R2 and n are as defined hereinabove with a compound R3Z wherein Z is halogen, OH, O-alkyl, OSO2-alkyl, OSO2-aryl, or an anhydride residue and R3 is as defined above, or by reacting a compound of the formula <FORM:1077173/C2/3> wherein Y is halogen, OH, OSO2-alkyl or OSO2-aryl with an amine of the formula <FORM:1077173/C2/4> wherein R1, R2, R3, and n are as defined above, and, if desired, forming a pharmaceutically acceptable acid addition salt thereof. Pharmaceutical compositions containing the above compounds and active in inhibiting the growth of protozoa are administered orally or parenterally. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8735425-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2658823-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006004200-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0445026-A1 |
| priorityDate | 1965-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.