http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1077089-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d269c8e41f178194d858c230c9f85e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-16 |
| filingDate | 1964-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea4850b2a554027d0af6e5ef8459bce3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ffb064e5069dba619bc14a7b4c496cb |
| publicationDate | 1967-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1077089-A |
| titleOfInvention | 1-substituted-3,4-dihydroisoquinolines |
| abstract | Novel compounds of the formula <FORM:1077089/C2/1> wherein R1, R2 and R3 are H or CH3, and X is H, C- 5 alkyl, C- 5 alkoxy or halogen, and the pharmaceutically acceptable acid addition salts thereof are prepared by cyclodehydration of an amide of formula <FORM:1077089/C2/2> wherein R1, R2, R3 and X are as defined, or by reaction of a phenoxyacetonitrile X.C6H4.O. CHR3.CN with a phenethyl chloride or bromide C6H5.CHR1.CHR2. Halogen, in the presence of SnCl4 as catalyst. The compounds have anti-viral activity. N - (p - chlorophenoxyacetyl) - b - phenyl ethylamine is prepared by reacting p-chlorophenoxyacetyl chloride and b - phenylethylamine. Pharmaceutical compositions comprise at least one compound of the first formula above, together with a pharmaceutically acceptable carrier. |
| priorityDate | 1964-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.