http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1068759-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-08 |
| filingDate | 1965-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1068759-A |
| titleOfInvention | Isoxazole compounds and salts thereof |
| abstract | Compounds of the general formula <FORM:1068759/C2/1> (wherein A represents an alkylene group containing not more than five carbon atoms, and R and R1 each represents a hydrogen atom or an alkyl group containing not more than five carbon atoms or R + R1 together represent a tetramethylene, pentamethylene, hexamethylene, oxatetramethylene, oxapentamethylene, oxahexamethylene, azatetramethylene, azapentamethylene, azahexamethylene, thiatetramethylene, thiapentamethylene or thiahexamethylene group), their acid addition salts and quaternary ammonium salts of those compounds in which the RR1N- group is tertiary amino group are prepared by reducing a compound of the formula <FORM:1068759/C2/2> with a metal hydride complex in an inert solvent, optionally followed by acid addition or quaternary ammonium salt formation. The preparation of a number of starting materials and of 3-phenyl-5-chloroacetylisoxazole is described. The compounds of the invention are antipyretic, analgesic, antitussive and anti-inflammatory agents, and may be administered in the form of pharmaceutical preparations containing them together with a carrier. |
| priorityDate | 1963-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 14.