http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1066409-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-91 |
| filingDate | 1966-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1066409-A |
| titleOfInvention | Novel imidazole derivatives and a process for the manufacture thereof |
| abstract | Novel compounds of the general formula <FORM:1066409/C2/1> wherein R represents the grouping <FORM:1066409/C2/2> in which X represents a hydrogen or a halogen atom or a hydroxy, alkanoyloxy group (1-7 carbon atoms) or alkoxy group (1-7 carbon atoms) and R1 represents a hydrogen atom or an alkanoyloxy group as above defined, and acid addition salts of those compounds which are basic are obtained in a process which comprises reacting 2-nitro-imidazole or a salt thereof with a base, with a compound of the formula <FORM:1066409/C2/3> wherein X1 represents a hydrogen or halogen atom or a hydroxy, alkoxy group (1-7 carbon atoms) or monosubstituted cleavable sulphonyloxy group to yield a compound of the formula <FORM:1066409/C2/4> cleaving off any sulphonyloxy group present and, if desired, any halogen atom present with the formation of a 2,3-epoxy-propyl group, hydrolysing or hydrogenating said 2,3-epoxy-propyl group if desired, lower alkanoylating any hydroxy-substituted product if desired, and also if desired, converting any basic product obtained into an acid addition salt. Pharmaceutical compositions containing the above compounds and active against bacteria, pathogenic yeasts and protozoa are administered orally, parenterally, or topically. |
| priorityDate | 1965-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.