http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1065126-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_334b26d249dc7a2d0df884c87eab5255 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-00 |
| filingDate | 1966-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1065126-A |
| titleOfInvention | Water-soluble derivatives of acylphenyl-acylamino-1,3-propanediols |
| abstract | Novel water-soluble acylphenylacylamino-1,3-propane-diols of Formula I <FORM:1065126/C2/1> wherein R is an alkyl, cyclopentyl, cyclohexyl or phenyl group, and R2 is a palmitoyl, palmitoyloxyacetyl or hemi-succinoyl group, are prepared by reacting an acylphenyl-acylamino-1,3-propanediol with succinic anhydride at about 80 DEG C. in the presence of substantially anhydrous pyridine over a period of about three hours, or by reacting the acylphenyl-acylamino - 1,3 - propanediol with palmitoyl or palmitoyloxyacetyl chloride at low temperature in anhydrous pyridine.ALSO:Therapeutic compositions, useful as urinary antiseptics which may be administered orally, contain as active ingredient compounds of formula <FORM:1065126/A5-A6/1> wherein R is an alkyl, cyclohexyl, cyclopentyl or phenyl group, and R2 is palmitoyl, palmitoyloxyacetyl or hemi-succinoyl, in association with a pharmaceutical carrier or other urinary antiseptics such as methenamine mandelate or other chemo-therapeutic agents such as sulpha drugs, the nitrofurans and colistin derivatives. |
| priorityDate | 1965-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.