http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1064293-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce010dfc8c8ee1224db9be853afeb081 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-333 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-333 |
| filingDate | 1963-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0a06ae771623bf84d90ab35d9cb0c0e |
| publicationDate | 1967-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1064293-A |
| titleOfInvention | Substituted 2-pyrrylketones |
| abstract | Novel compounds of the Formula I, wherein R1 represents a hydrogen atom, a straight or branched chain-alkyl radical, or an aryl, aralkyl, alkaryl, alkoxyaryl or aryloxyalkyl radical, optionally substituted by a halogen atom or a heterocyclic radical, R2 and R3, the same or different, represent hydrogen atoms or C1- 5 alkyl radicals, R4 and R5, the same or different, represent C1- 5 alkyl radicals or together, with the nitrogen atom to which they are attached, form a heterocyclic radical, and n represents 0 or 1, and their pharmaceutically acceptable non-toxic acid addition salts, are prepared by reacting a halogenated tertiary amine of the formula X-CHR2.CHR3.(CH2)n.NR4R5 wher X represents a halogen atom with a compound of the formula II <FORM:1064293/C2/1> 2 - (4 - Methoxybenzoyl)pyrrole may be prepared by the action of anisoyl chloride on the magnesium derivative of pyrrole. 2 - (a - Ethylbutyryl)pyrrole may be prepared by the action of diethylacetyl chloride on the magnesium derivative of pyrrole. Therapeutic compositions with anti-tussive, spasmolytic, anti-histaminic, local anaesthetic or respiratory analeptic properties comprise compounds of the Formula I or their pharmaceutically acceptable, non-toxic acid addition salts together with a non-toxic pharmaceutical carrier. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8393334-B2 |
| priorityDate | 1963-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.