http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1062448-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f6a6487902840957ea22664781405d8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 |
filingDate | 1964-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c685450baeb1524d99322036752c9bc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e44a2033257c80cce11f2b1e76459f17 |
publicationDate | 1967-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1062448-A |
titleOfInvention | Derivatives of uracil and method of preparing the same |
abstract | New compounds of Formula I <FORM:1062448/C2/1> where R1 is lower (i.e. 1-6 C) alkyl or b -chloroethyl, R2 is alkyl, cycloalkyl, aralkyl, alkenyl or aryl, and X is hydrogen or chlorine, and their pharmaceutically acceptable acid addition salts, are prepared by chlorination of compounds II where R3 is lower alkyl or b -hydroxyethyl <FORM:1062448/C2/2> (preparable from uracils, HCHO and R3NHCH2CH2OH): also described is hydrogenation to replace a chlorine atom X. Pharmaceutical compositions comprise the new compounds with carriers, being useful as cytostatic agents. |
priorityDate | 1964-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.