http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1061717-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1963-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1061717-A |
| titleOfInvention | A process for the preparation of water-insoluble derivatives of acylase |
| abstract | A water insoluble derivative of acylase (see Division C3) is used to cause asymmetric hydrolysis and optical resolution of N-acyl-DL-amino acids to produce optically active amino acids. Examples relate to the production of L-valine and L-alanine from the N-acetyl derivatives of the DL acids. Other acids mentioned are leucine, glutamic acid, methionine, phenylalanine (all in N-acetyl form) and lysine (in e -N-benzoyl-a -N-acetyl form).ALSO:A water-insoluble acylase derivative is produced by reacting acylase with an N-carboxy-a -amino anhydride and/or an N-carboxy-a -amino anhydride having a second carboxylic acid group (not adjacent to the amino group) which may be esterified. Specified reactants are the N - carboxy - a - amino acid anhydrides of a - amino n - butyric acid, valine, leucine, isoleucine, phenyl alanine, a b -methyl-, ethyl- or benzyl-ester of aspartic acid or a g -ester of glutamic acid. Co+ + +, Ca+ + or Zn+ + ions or cysteine may be present as an acylase inactivator. The product is useful in resolving DL amino acids by asymmetric hydrolysis (see Division C2). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4224411-A |
| priorityDate | 1962-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.