http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1061687-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-568 |
filingDate | 1965-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1967-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1061687-A |
titleOfInvention | 3-amino-5-androstene compounds |
abstract | The invention comprises steroids of the formula <FORM:1061687/C2/1> (wherein R is hydrogen, A or A.CO and R1 and R11 are hydrogen or A, A being C1- 7 alkyl) and the preparation of the 3b -amino-17b -carbalkoxyandrost-5-enes by reacting a 6b -alkoxy-17b -carbalkoxy-3a ,5a -cycloandrostane with hydrazoic acid in a non-polar, inert, anhydrous, organic solvent and in the presence of an acid catalyst, separating the formed 3b -azido-17b -carbalkoxyandrost-5-ene and reducing this. The products can be acylated or alkylated at the amino group and hydrolysed to 17b -carboxy-compounds which can be re-esterified. Examples are given. 6b - Methoxy - 17b - carbomethoxy - 3a ,5a - cycloandrostane is prepared by refluxing 3b -p-toluenesulphonyloxy - 17b - carbomethoxy - androst-5-ene with sodium acetate and methanol. |
priorityDate | 1964-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.