http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1058828-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09fa84c54c24536575f7f12c1f1db43 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-006 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 1963-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1967-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1058828-A |
| titleOfInvention | Process for the manufacture of artificial antigens |
| abstract | Artificial antigens are produced by linking a carrier protein via an organic bridge group to a serologically determinant peptide, e.g. a protein hormone, toxin, enzyme or a virus or bacterium having a surface component with protein characteristics. The linkage may be formed by a chemical process such as forming a diazo or azide derivative of one component which is coupled to the phenolic hydroxyl or amine groups of the other or by cross-linking the two components by reaction with a diisocyanate. The specific example relates to a product obtained by formation of a diazo group-containing derivative of a C-terminal hexapeptide obtained by enzymatic digestion of tobacco mosaic virus and coupling with a diisocyanate-cross -linked cattle albumin. Suitable carrier proteins are egg albumin, serum albumin, lactalbumin, g -globulins and gelatin and its derivatives.ALSO:Artificial antigens are produced by linking a "carrier protein" via an organic bridge group to a serologically determinant peptide. Suitable carrier proteins are: egg albumin, lacta bumin, serum albumin, g -globulins and gelatin and its derivatives. The serologically determinant peptide may be a protein hormone, toxin, enzyme or a virus or bacterium whose surface component has protein characteristics. The linkage may be formed by a chemical process such as (1) forming a diazo derivative of one component, which is coupled to a phenolic hydroxyl group of the other, (2) by similarly forming an azide of one component, which is coupled to the amino group of the other or (3) by cross-linking the two components by reaction with a diisocyanate. The specific example relates to a product obtained by formation of a diazo derivative of a C-terminal hexapeptide obtained by enzymatic digestion of the tobacco mosaic virus and coupling with a diisocyanate cross-linked cattle albumin. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0095426-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0094844-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447383-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2646223-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4587046-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104383889-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2527445-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6146633-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0094844-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2421943-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104383889-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2532850-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447383-B |
| priorityDate | 1963-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.