http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1055619-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-1854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-1827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-42 |
| filingDate | 1964-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b574a009d49e09f4387a69a050a45c66 |
| publicationDate | 1967-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1055619-A |
| titleOfInvention | Urea derivatives |
| abstract | The invention comprises compounds of formula <FORM:1055619/C2/1> wherein R is H, alkyl, cycloalkyl or alkenyl, or (optionally nuclear halogen-, alkyl- or alkoxy-substituted) aralkyl, aralkenyl or aryl, and X and Y are halogens, at least one of which is Br or I; ring A may be alkyl-substituted or it may be part of a naphthalene ring. These compounds are prepared by (a) hydrolysing a 3-(XY-substituted) arylquinazolin-2,4-dione to give a product where R = H, (b) reacting CO2R-substituted phenyl isocyanate with XY-substituted aniline or (c) reacting CO2R-substituted aniline with XY-substituted phenyl isocyanate. The invention includes pharmaceutically-acceptable salts.ALSO:Ureas which are stated to be useful in the treatment of allergic and inflammatory conditions, have the formula: <FORM:1055619/A5-A6/1> wherein R is H, alkyl cycloalkyl or alkenyl, or (optionally nuclear halogen-, alkyl- or alkoxy-substituted) aralkyl, aralkeryl or aryl, X and Y are halogens of which at least one is Br or I and ring A may be alkyl-substituted or it may be part of a naphthalene ring; pharmaceutically acceptable salts are included. The compounds may be formulated, with the usual diluents, carriers and additives, as tablets, capsules, aqueous or oily emulsions or suspensions, or dispersible powders. Known anti-inflammatory agents such as acetylsalicyclic acid, phenylbutazone or steroids, e.g. cortisone or hydrocortisone may be included. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5093367-A |
| priorityDate | 1964-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.