http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1031080-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e96c741ab01e3262a37ca941cf36fd4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
filingDate | 1963-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1966-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1031080-A |
titleOfInvention | Improvements in or relating to 16-aminomethyl-17-alkyl-testosterone and -isotestosterone derivatives |
abstract | The invention comprises compounds of formulae <FORM:1031080/C2/1> wherein R is a methyl or ethyl group and R1 and R2 are C1- 6 alkyl groups or -NR1R2 forms a heterocyclic amino-group, acid addition and quaternary ammonium salts thereof, and their preparation by reaction of a corresponding 3 - hydroxy - 17 - keto - compound with a Grignard reagent followed by hydrolysis and, if desired, by oxidation to the corresponding 3-keto compound. The compounds of the invention have anti-anabolic and anti-androgenic activity and may be used in pharmaceutical compositions in combination with a carrier, for example in forms suitable for oral or parenteral administration, such as tablets, capsules, pills, troches, solutions and suspensions. |
priorityDate | 1962-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458393636 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458393705 |
Total number of triples: 14.