http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1027618-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e737b999245afb461a9a9e552e8f3a1e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 |
| filingDate | 1964-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_022b20d12753f16d3fac9bd433e91f24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb9c75dfdcc0f27064b556a0c693e30b |
| publicationDate | 1966-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1027618-A |
| titleOfInvention | Improvements in or relating to d-homo steroids |
| abstract | The invention comprises D-homo-aromatic steroids having the formula: <FORM:1027618/C2/1> wherein R and R4 are H, OH, O-alkyl, O-cycloalkyl (containing up to 12 carbon atoms) or lower alkyl (containing up to 3 carbon atoms) and may be the same or different, R1 is H or a lower alkyl group containing up to 3 carbon atoms, R2 is H, lower alkyl containing up to three carbon atoms, halogen CH2OH or CF3 and wherein additional double bonds may be present in ring B and lower alkyl or methylene groups may be present in rings B, C and D, and the preparation thereof by condensing the corresponding D-homo-17a -oxo steroid having the formula: <FORM:1027618/C2/2> with metallic, including Grignard types of metallic, derivatives of the appropriate ethyne, e.g. with sodium chloracetylide in liquid ammonia or trifluopropynylmagnesium bromide in ether-tetrahydrofuran. Pharmaceutical compositions valuable as claudogenic agents and containing the above compounds are administered orally as suspensions or tablets, or as injections or suppositories. |
| priorityDate | 1964-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.