http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1027617-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_049564710b730d1d25ef3f2c20c2e5ac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-00 |
| filingDate | 1963-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b58fe20b4906e37490ad7e046e9e0a |
| publicationDate | 1966-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1027617-A |
| titleOfInvention | Derivatives of tetracycline-type compounds |
| abstract | The invention relates to 2-carbonamido-substituted tetracyclines of formula <FORM:1027617/C2/1> wherein TC1 is a monovalent radical derived from a tetracycline-type compound (defined) by removal of one hydrogen from the carbon-amido group thereof: X is a cation selected from H, alkali metals, alkaline earth metals and basic antibiotics; n is a number equal to the valency of X and R is -OH or TC2 wherein TC2 is a monovalent radical derived from a tetracycline-type compound as above by removal of one H from the carbonamide group and wherein TC1 and TC2 are the same or different. The basic antibiotic may be tetracycline, erythromycin, streptomycin, novobiocin, polymyxin, benzylpenicillin 2-diethylaminoethyl ester, chloramphenicol glycinate or thiamphenicol glycinate. The tetracycline-compound is reacted with glyoxylic acid in the presence of a tertiary N base. Typical compounds are tetracycline glycollic acid and tetracycline glycollate of erythromycin. Oral, topical and parenteral compositions comprise an antibiotic as above and a carrier. |
| priorityDate | 1963-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.