http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1011288-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87d885f21dead30ee1fa8a1265d3860f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B55-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-26 |
filingDate | 1962-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1965-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-1011288-A |
titleOfInvention | Benzoxazine-2:4-dione derivatives and a process of making same |
abstract | The invention comprises compounds of formula <FORM:1011288/C2/1> wherein each of R1 and R2 represent a hydrogen atom, an alkyl radical having 1 to 6 carbon atoms, an esterified carboxyl group, a carbamoyl radial substituted by (a) an alkyl, haloalkyl, or unsaturated alkyl group, all containing up to 6 carbon atoms, or (b) an aryl or aralkyl radical, an aryl group, optionally halo-substituted, or a radical of formula <FORM:1011288/C2/2> wherein R3 and R4 are each a hydrogen atom, an alkyl radical having up to 6 carbon atoms or an aryl radical or R3 and R4 form, in combination with the nitrogen atom to which they are attached, a 5- or 6-membered ring which may be interrupted by an oxygen atom or an optionally alkylated nitrogen atom, present in the para-position in the case of a 6-membered ring, and R5 is a hydrogen atom, an alkyl group having up to 6 carbon atoms or an amino-group, or wherein R1 and R2 together form the radical =CH-R6 in which R6 is a heterocyclic radical, acid addition salts thereof, and their preparation by reduction of the compound of formula <FORM:1011288/C2/3> followed, if desired, by mono- or di-substitution of the amino-group formed. The compounds of the invention have analgesic, muscle-relaxant, reflex inhibition and temperature-decreasing activity. The 6-nitro-dihydro-1,3-benzoxazine-2,4-dione used as the starting material above is prepared by nitration. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114672020-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114672020-B |
priorityDate | 1961-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.