http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1008168-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5922cbe7c65a9136f85906fa09e7c967 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1963-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1008168-A |
| titleOfInvention | Production of 19-hydroxy-steroids |
| abstract | 19-Hydroxy-D 4-3-keto-steroids are prepared by reacting the corresponding 3,19-dihydroxy-D 5-steroids with an aluminium alkoxide containing up to 6 carbon atoms in the alkyl radical and an aliphatic, alicyclic or aromatic ketone of up to 13 carbon atoms inclusive in a non-polar organic solvent at reflux temperature for an approximate time of 5 to 15 minutes. The steroids may belong to the pregnane, androstane or sapogenin series and may contain at position 17 a keto group, a 17b -acyloxy group, a 17b -hydroxy group with or without a 17a -substituent, a 17a -acyloxy group, a dihydroxyacetone side a 17a -acyloxy group, a dihydroxyacetone side chain preferably protected as a 17, 20; 20, 21-bismethylenedioxy group or a sapogenin sidechain; at position 11 a keto or hydroxy group; at position 16 a keto, hydroxy or methyl group; and a D 16-double bond. The preferred solvent is toluene, and the preferred ketone cyclohexanone. Examples are given. Specifications 820,780, 853,851 and 1,004,463 are referred to. |
| priorityDate | 1962-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.