http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-1003113-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_404c787d6b2e4d3f135ee391f79199a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-18 |
| filingDate | 1963-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-1003113-A |
| titleOfInvention | 3,4-dihydro-benzoxazinones-(1,3,2) and processes for the production of such compounds |
| abstract | The invention comprises 3,4-dihydro-benzoxazinones of the formula I <FORM:1003113/C2/1> wherein R represents hydrogen, methyl or ethyl and wherein the benzene ring can carry one or more chlorine, bromine, methyl, chloromethyl, nitro and/or amino substituents, with the proviso that if the benzene ring is unsubstituted or if it carries only a methyl group in each of the 6- and 8-positions, R represents methyl or ethyl; and a process for the production of compounds of the formula I, wherein R represents hydrogen, methyl or ethyl and wherein the benzene ring can carry one or more chlorine, bromine, methyl, chloromethyl, nitro and/or amino substituents by reacting a 2-hydroxybenzyl halide of the formula II <FORM:1003113/C2/2> wherein X represents chlorine, bromine or iodine and wherein the aromatic nucleus must carry at least one chlorine or bromine atom or nitro group and may carry further chlorine or bromine atoms, methyl, chloromethyl and/or nitro groups, with a salt of cyanic acid, and if the compound thus produced contains one or more reducible substituents, optionally these may be treated to split off reductively any chlorine or bromine atoms, and/or to reduce any nitro groups to amino groups. The salt of cyanic acid, e.g. the alkali or alkaline earth metal salt, may be produced in situ, for example by using a cyanide in the presence of an oxidation agent, or with urea and an alkali. 2-Hydroxybenzyl halides of formula II may be prepared by halogenating a corresponding 2-hydroxytoluene in the side chain, or treating a corresponding 2-hydroxybenzyl alcohol with a hydrogen halide or an inorganic acid halide, or subjecting an appropriate phenol to a chloromethylation in the o-position. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016540810-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3627762-A |
| priorityDate | 1962-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.