abstract |
The invention relates to a composition, in the form of an aqueous solution, comprising insulin in hexameric form, and at least one substituted citrate of Formula I: in which: - R1, R2, R3 identical or different, represent OH or AA, - at least one of R1, R2, R3 is a radical AA, - AA is a radical derived from a natural or synthetic aromatic amino acid comprising at least one phenyl group or an indole group, substituted or unsubstituted, said AA radical having at least one free carboxylic acid function, the carboxylic acid functions are in the form of an alkali metal salt selected from Na + and K +. |