abstract |
The present invention relates to a molecular signature of the actinic lentigo specific for Asian skin, comprising the genes LCE3D, SPRR2B, SPRR2G and SPRR3, and various applications of this signature. The invention particularly relates to a method for characterizing an apparent pigment spot in a human with Asian skin, comprising comparing the levels of expression in skin samples from said stain and adjacent skin that has not been injured. Genoa. The invention also relates to methods for evaluating the efficacy of a specific treatment of actinic lentigo present on Asian skin, cosmetic methods of treating actinic lentigo present on Asian skin, as well as various modulators of said genes and their use. |