http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3008106-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fd9074e7f5629511f3a410b1316b5f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2013-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1771d3af2bd9582558c9e742ef2548b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_253690744d3dba997e51d5ebe0279139 |
| publicationDate | 2015-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-3008106-A1 |
| titleOfInvention | METHOD OF INDUCING A TARGETED MEIOTIC RECOMBINATION |
| abstract | The invention relates to a method for inducing targeted meiotic recombination in a eukaryotic host cell, by co-expressing in said cell a first ME chimeric protein comprising an effector domain DE capable of inducing the formation of double-strand breaks. strand in the DNA during meiotic recombination and a DI1 interaction domain consisting of the first partner of a protein-protein selective affinity couple, and a second chimeric protein comprising a DI2 interaction domain consisting of the second partner of said protein-protein selective affinity pair and a DC targeting domain capable of selectively binding to a target sequence present in the DNA of said host cell. The protein-protein interaction between the DI1 and DI2 domains allows the formation of a non-covalent complex between the ME module and the MC module, and the induction of double-strand breaks by the DE effector domain near the targeted sequence by the DC targeting domain. |
| priorityDate | 2013-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.