http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3003172-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f6be7b5f316f050e9151b3afd8936f7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69c3bc4a43030ae1232de13fe8a3ed22 |
| publicationDate | 2014-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-3003172-A1 |
| titleOfInvention | USE OF MONOCLONAL ANTIBODIES FOR THE TREATMENT OF INFLAMMATION AND BACTERIAL INFECTIONS |
| abstract | The present invention relates to a composition comprising monoclonal antibodies directed against a circulating pro-inflammatory cytokine, said antibodies having a strong affinity for the FcγRIIIa receptor (CD 16), in particular the fucose level of all the antibodies of said composition being less than 60%, and preferably less than 50%, and in particular, the level of galactosylation of all the antibodies of said composition being at least 60%, for use in the context of prevention or treatment early stages of inflammation. The present invention also relates to a composition comprising monoclonal antibodies directed against a circulating bacterial toxin, having an affinity for the FcγRIIIa receptor (CD 16) improved compared to antibodies directed against said bacterial toxin, produced in the CHO cell line, for use in the prevention or treatment of early stages of a bacterial infection related to release of said toxin. |
| priorityDate | 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 207.