http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2988843-A1

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filingDate 2012-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88cb0292f4ffc08a12bca6cceb792634
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publicationDate 2013-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber FR-2988843-A1
titleOfInvention METHOD FOR DETERMINING THE TUMOR OR NON-TUMOR NATURE OR TYPE OF TUMOR OF A HUMAN OR ANIMAL SOLID MEMBER FRAGMENT
abstract The present invention relates to a method for determining the tumor or non-tumor nature or the type of tumor and / or cancer type of a human or animal solid organ fragment of a given individual, by spectrum analysis (FIG. ) of MALDI-TOF type mass spectrometry, said type of tumor belonging to at least one class or subclass of tumors, characterized in that the following successive steps are carried out in which: 1) a first sample of a homogenous homogenous suspension of said fragment comprising a mixture of different types of non-lysed whole cells, and 2) at least one spectrum of at least one said first sample is made and said spectrum is analyzed in comparison with at least one a reference profile, said reference profile being constituted by at least one list of reference peak (s) of spectrum (s) established (s) on reference fragments being known to be tumor-type or non-tumor ale, or, in case of tumor, being known to belong to a said class or subclass of tumor or cancer, and 3) it is determined whether said tissue fragment of said first sample is a tissue fragment of tumor nature or not tumor or belongs to a said class or subclass of tumor or cancer, according to the presence or absence of said reference peaks and / or the value of the area of said reference peaks in the spectrum of said first sample.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3009089-A1
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