abstract |
The present invention relates to peptide compounds of general formula (I) R1 - (AA) n - X1 - X2 - Ile - Gln - Ala - Cys - Arg - Gly - X3 - (AA) p - R2 as activators of caspase-14. In addition, the present invention relates, on the one hand, to a cosmetic or pharmaceutical composition, comprising at least one peptide of general formula (I), in a physiologically acceptable medium and, on the other hand, its use to prevent and / or repair damage to DNA, prevent and / or treat skin signs of aging and photo-aging and improve the barrier function of the skin. The invention finally relates to a cosmetic treatment method for preventing and / or treating the cutaneous signs of aging and photo-aging, and preventing and / or repairing the damage caused by UV radiation. |