http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2949789-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate | 2009-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c91fab27cab5b8603874e5e2aca96a93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_814670c1da1dcfe031805c4b8ef1bae6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3a3089fa4be26d1f104edb4603acf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b210eeaf4f999966bb93dc3881c9944a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_727402874a27db3c0724b39cbb9cbc12 |
| publicationDate | 2011-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2949789-A1 |
| titleOfInvention | IDENTIFICATION OF CELLULAR TROPISM OF VIRUSES |
| abstract | The invention relates to an in vitro method for identifying microRNAs, or their target mRNAs, whose expression, during infection of cells with a virus using a cellular receptor and at least one cellular co-receptor to enter the cell is specifically modified according to the cellular co-receptor used by the virus for its entry into the cells, comprising: i) determining the expression levels of microRNAs in a test cell, expressing a receptor, a first co-receptor and at least one other co-receptor, after infection respectively with a first virus using the first co-receptor and with at least one other virus using another co-receptor; ii) identify microRNAs whose level of expression is modulated upon infection by each of the viruses relative to the level of expression in uninfected cells; iii) compare the microRNAs identified in this way; iv) select microRNAs whose modification of the level of expression is specific to the use of a co-receptor; v) optionally identify the target mRNAs of the microRNAs thus selected. |
| priorityDate | 2009-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.