| abstract |
The present invention relates to a dipeptide conjugate of the following general formula I AA2-AA1-NH in which A represents the radical corresponding to a monocarboxylic acid of general formula II following HOOC-R in which R represents a linear or branched C -C aliphatic radical optionally substituted by a hydroxyl group, which may comprise one or more unsaturations, advantageously from 1 to 6 unsaturations, and / or may comprise a phenyl group or lipoic acid or its reduced form, dihydrolipoic acid or N-lipoyl-lysine , AA1 and AA2 represent identical or different amino acids selected from the group consisting of Ala, Asn, Cys, Gln, Gly, Ile, Leu, Met, Phe, Pro, Ser, Thr, Trp, Tyr, Val, Asp, Glu , Arg, His, Lys, Orn, Dap, Dab the corresponding amino homoacids and the corresponding beta-amino acids in the form of enantiomers or diastereoisomers and mixtures thereof, including racemic mixtures. ues. |