| abstract |
The present invention relates to a peptide of general formula (I): R - (AA) -X -Gly-Glu-Leu-Ser-X-X (AA) -R, derived from human HMG-CoA reductase. The present invention also relates to a cosmetic or pharmaceutical composition, comprising at least one peptide of general formula (I), in a physiologically suitable medium. The present invention also relates to the use of this novel peptide, as an activating active ingredient of human HMG-CoA reductase, in a cosmetic composition intended to enhance the cutaneous barrier function and to stimulate epidermal differentiation. The invention also relates to a cosmetic treatment method for preventing and / or combating external aggressions and the manifestations of skin aging. |