| abstract |
The invention relates to tropane urea derivatives of general formula (I) wherein A represents a bond or a group -O- (CH) - where n is a number equal to 0 or 1, D represents a bond or atom oxygen, G represents a carbon or nitrogen atom, Ar1 represents an aryl or heteroaryl group, Ar2 represents an aryl or heteroaryl (pyridine) or heterocycloalkyl group, R1 represents a hydrogen atom, a (C1-C6) group, ) alkyl, -SO- (C1-C6) alkyl, -SO-halo (C1-C6) alkyl or (C1-C6) alkoxy, R2 represents a hydrogen atom or a hydroxy group or, when G is a hydrogen atom; nitrogen, R2 is absent, R3 represents a hydroxy group or -C (O) -NH, Preparation process and application in therapy. |