| abstract |
The invention relates to new products of formula (I): g id="ID2932484-9" he="" wi="" file="" img-format="tif"/> > with Het represents an aromatic heterocycle or partially unsaturated, mono or bicyclic, containing from 1 to 4 N, O or S heteroatoms, optionally substituted by identical or different R1 or R'1; R represents X-(A-B)n-CONH2, X-(A-B)n-O-CONH2, X-(A-B)n-NH-CONH2, X-(CH2)m-heterocycloalkyl, X-(CH2)m-aryl and X -(CH2)m-heteroaryl with X representing -O-C(O), -NH-C(O), NH-CS, -NH-CO-CH2-O-; -NH-CO-CH2-S-CH2-CO-NH-; -NH-CO-(CH2)2-SO2-; -NH-CO-CH2-N(CH3)-CO-; A and B, identical or different, independently represent a single bond, CH2, CH-alkyl, CH-aralkyl, n=1.2 and m=0.1; R1 and/or R'1 represent H, halogen, CF3, nitro, cyano, alkyl, hydroxy, mercapto, amino, alkylamino, dialkylamino, alkoxy, alkylthio, carboxy free or esterified by an alkyl radical, carboxamide, CO-NH(alkyl ), CON(alkyl)2, NH-CO-alkyl, sulfonamide, NH-SO2-alkyl, S(O)2-NHalkyl, S(O2)-N(alkyl)2, all these alkyl, alkoxy and alkylthio radicals being themselves optionally substituted; these products being in all the isomeric forms and the salts, as medicaments. |