| abstract |
The present application relates to a new class of terpene-derived compounds, having an antibiotic activity, of formulas (I) or (II) in which A is selected from NR1, O, S, CR2R3 or R- (CH2) nR 'in which R and R 'are, independently of one another, NH, O, S or CH2, and R1, R2 and R3 are substituents, and n is greater than or equal to 1, in particular equal to 2.The demand both the compound in its formula (I) or in its formula (II) taken individually, the mixtures of these two compounds, as well as compositions, including therapeutic, comprising at least one of these compounds or this mixture. In a particular embodiment, the compound (I) or (II) taken individually, the mixtures of these two compounds as well as the compositions of the invention are used in the treatment of C. difficile-related digestive infections. of particular embodiment, the compound of formula (I) is margaucine, a compound produced by a bacterial strain. |